BOOKS / 出版物

The Winding Road to Discovering iPS Cells

The Winding Road to Discovering iPS Cells

The Life of Yamanaka Shinya

Yamanaka Shinya, Interviewer Midori Shinya
Translated by Tony Atkinson

Future Titles / Science

To be published by JPIC | ISBN 978-4-86658-177-4 (Hardcover) | *** pages | 210mm (h) x 148mm (w) | March 2021

※Information for this title is still tentative and subject to change prior to publication

About the Book

The revolutionary discovery of induced pluripotent stem cells, or iPS cells, completely changed the world, particularly in the field of medical science. This groundbreaking achievement was made by Dr. Yamanaka Shinya of Kyoto University and won him the Nobel Prize for Physiology or Medicine in 2012.

The road that led him to this accomplishment, however, was not an easy one; during his early days as a training orthopedic surgeon, Yamanaka was not skilled and was called “a hindrance” by his supervisor. He eventually changed course to become a researcher and worked as a postdoctoral researcher in the United States, but he experienced a mild case of depression upon returning to Japan. Even when Yamanaka presented the results of the newly discovered iPS cells, he could not immediately bask in the glory of his success, since many people simply could not believe his achievement.

In this volume, the Nobel Prize laureate talks openly about his life from his childhood days to his current daily life and discusses his views on the future of regenerative medicine. How were iPS cells developed and what can they do? Translated from a runaway bestseller in Japan and replete with a new foreword for the English edition, this biography shows what science can do for mankind, and the possibilities that life holds.

About the Author

YAMANAKA Shinya

Dr. Yamanaka Shinya is the director of the Center for iPS Cell Research and Application (CiRA) at Kyoto University. In 2006 his team succeeded in generating iPS cells from mouse skin cells. The following year his team developed human iPS cells from human skin cells. For this achievement, he was awarded the 2012 Nobel Prize for Physiology or Medicine.

MIDORI Shinya

Midori Shinya is a science journalist. His works include Kieta densetsu no saru Benz (Benz, a missing legendary monkey, 2015), Uirusu daikansen jidai (The age of widely infectious diseases, co-authored with NHK Special reporting team, 2017), among others.

内容紹介

山中先生が初めて語った、「iPS細胞ができるまで」と「iPS細胞にできること」。「ジャマナカ」と蔑まれた研修医時代、臨床医から研究者への転向、留学後にかかった「アメリカ後うつ病」、発見を認めてもらえないもどかしさ、熾烈な「ヒトiPS細胞」開発競争―そして山中先生が見つめる再生医療の未来とは?やさしい語り口で中学生から読める、山中先生の人生と科学の可能性!

著者紹介

山中伸弥
1962年大阪市生まれ。神戸大学医学部卒業、大阪市立大学大学院医学研究科修了(博士)。米国グラッドストーン研究所博士研究員を経て、96年大阪市立大学医学部助手、99年奈良先端科学技術大学院大学遺伝子教育研究センター助教授、2003年同教授、04年京都大学再生医科学研究所教授、08年京都大学物質―細胞統合システム拠点iPS細胞研究センター長、2010年4月から京都大学iPS細胞研究所所長。

胚性幹細胞(ES細胞)と異なり、受精卵を用いずにさまざまな組織に分化する可能性を持つ人工多能性幹(iPS)細胞をマウスの皮膚細胞から作り出すことに成功、新たな研究領域の開拓者となる。同じ方法で07年ヒトの皮膚細胞からiPS細胞を作り出すことにも成功した。コッホ賞(08年)、ラスカー賞(09年)、京都賞(10年)、ウルフ賞(11年)など受賞多数。2012年、ノーベル医学生理学賞を受賞。

緑 慎也

1976年大阪市生まれ。出版社勤務、月刊誌記者を経てフリーに。科学技術を中心に取材・執筆活動を続けている。単行本構成に『戸塚教授の「科学入門」』(戸塚洋二・講談社)、『がん 生と死の謎に挑む』(立花隆、NHKスペシャル取材班・文藝春秋)。聞き書きに『のたうつ者』(挾土秀平・毎日新聞社)など。

Original Japanese Edition / 原書情報

山中伸弥先生に、人生とiPS細胞について聞いてみた

山中伸弥先生に、人生とiPS細胞について聞いてみた

山中 伸弥 著

講談社 刊

2017/07/21

https://bit.ly/39TKEoA